From Sunday 27 February, the station entrance, travel centre and bus stands are being relocated to the other side of the site, near the Sunday School Façade and Sainsbury’s on Winding Road.
Services 586 and 587, 226, 348 and 349 will also move to town centre bus stops from that date.
Most bus services will run from the town centre during the day with some evening services returning to the station from 7pm. A small number of services are remaining on site throughout.
Passengers are being asked to visit www.wymetro.com/halifaxbusstationworks or call 0113 245 7676 for travel information.
Posters detailing where to catch buses and how to find out more about the project will be displayed at the bus station, on buses, and on key buildings and bus stops across the town centre.
Staff will also initially be on hand at the bus station and on-street to help people and answer questions.
During this latest phase of works, which is expected to last until summer 2023, the cash and vending machines, as well as the photobooth, will be unavailable.